Podoconiosis  

Oleh:

Lapolla, Whitney ; Tyring, Stephen K.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 364 no. 12 (Mar. 2011), page 364:e23.
Topik: Skin Nodules; Wuchereria Bancrofti; Filaria
Fulltext: Podoconiosis.pdf (99.64KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2011.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

A 36-year-old man presented to an Ethiopian clinic with a 20-year history of skin nodules, pain, and edema involving his legs and feet. He was otherwise healthy and worked as a farmer. Circulating filarial antigen tests for the presence of Wuchereria bancrofti were negative; he was not tested for other types of filaria. This clinical presentation prompted a diagnosis of probable podoconiosis (also known as nonfilarial elephantiasis or mossy foot). This locally endemic, noninfectious condition is caused by the long-term exposure of susceptible persons to irritant volcanic soil. Colloid particles are thought to be absorbed through the skin and taken up by macrophages, leading to lymphatic fibrosis and elephantiasis. Affected persons are typically barefoot agricultural workers in the highland tropics. Social stigma associated with this condition is widespread; patients are banned from schools, churches, and marriage. Economic productivity is often impaired. Podoconiosis is preventable with fastidious shoe wearing and foot hygiene. Treatment is limited to compression bandaging and elevation. The patient was instructed to wear shoes, but additional nodules continued to develop on uncovered areas of his sandaled feet.

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