Cardiac Development and Implications for Heart Disease  

Oleh:

Epstein, Jonathan A.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 363 no. 17 (Oct. 2010), page 1638-1647.
Topik: CARDIOVASCULAR DISEASES; Heart Disease; Myocardial Precursor Cells; Embryonic Stem

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Franklin H. Epstein, M.D., served the New England Journal of Medicine for more than 20 years. A keen clinician, accomplished researcher, and outstanding teacher, Dr. Epstein was Chair and Professor of Medicine at Beth Israel Deaconess Medical Center, Boston, where the Franklin H. Epstein, M.D., Memorial Lectureship in Mechanisms of Disease has been established in his memory. During the past decade, our understanding of the development of the embryonic heart has been improved by a number of discoveries. These new findings will require changes in standard teachings of how the four-chambered heart forms, and they have implications for the management of congenital and acquired heart disease. In the coming years, additional advances in our knowledge of cardiac development are likely to further influence the classification and treatment of congenital heart disease, inform clinicians on the best uses of regenerative treatment (e.g., stem-cell therapy), and revise our understanding of some cardiovascular disorders in adults. This review gives examples of recent findings in the field of cardiac development, with an emphasis on those likely to have the greatest effect on clinical practice.

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