Comparisons of inhibin B versus antimüllerian hormone in poor ovarian responders undergoing in vitro fertilization  

Oleh:

Tan, Rongrong ; Pu, Danhua ; Liu, Lipeng ; Liu, Jiayin ; Wu, Jie

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 96 no. 04 (Oct. 2011), page 905-911.
Topik: Antimullerian hormone; in vitro fertilization; inhibin B; poor ovarian response; meta-analysis

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2011.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To evaluate serum inhibin B as a predictor of poor ovarian response in patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) and to compare it with the performance of antimüllerian hormone (AMH). Design Meta-analysis. Setting University hospital. Patient(s) Patients undergoing IVF. Intervention(s) None. Main Outcome Measure(s) Poor ovarian response in controlled ovarian hyperstimulation (COH). Result(s) Fifteen studies on serum inhibin B and 12 studies on AMH were selected for meta-analysis. Both basal and stimulated inhibin B levels were statistically significantly lower in poor ovarian responders than in controls. The estimated summary receiver operating characteristic (ROC) curves suggested that stimulated inhibin B was more accurate than basal inhibin B and AMH in the prediction of poor ovarian response. Conclusion(s) Both basal and stimulated serum inhibin B levels are lower in poor responders than in controls. Compared with AMH, stimulated inhibin B is a more accurate predictor of ovarian response in patients undergoing IVF, making it a potentially useful tool in future IVF practice.

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