Maternal Care and Individual Differences in Defensive Responses  

Oleh:

Parent, Carine ; Zhang, Tie-Yuan ; Caldji, Christian ; Bagot, Rose ; Champagne, Frances A. ; Pruessner, Jens ; Meaney, Michael J.

Jenis: Article from Journal - e-Journal
Dalam koleksi: Current Directions in Psychological Science vol. 14 no. 05 (Oct. 2005), page 229-233.
Topik: maternal care; stress responses; epigenesis; stress hormones; individual differences
Fulltext: 01. Maternal Care and Individual Differences in Defensive Responses.pdf (124.22KB)

Isi artikel

Familial transmission of mental illness is common. Recent studies in behavioral neuroscience and biological psychiatry reveal the importance of epigenetic mechanisms of transmission that center on the developmental consequences of variations in parental care. Studies with rats suggest that environmental adversity results in patterns of parent–offspring interactions that increase stress reactivity through sustained effects on gene expression in brain regions known to regulate behavioral, endocrine, and autonomic responses to stress. While such effects might be adaptive, the associated cost involves an increased risk for stress-related illness.

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