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Maternal folic acid supplement intake and semen quality in Danish sons: a follow-up study
Oleh:
Jacobsen, Kristoffer
;
Ramlau-Hansen, Cecilia Host
;
Thulstrup, Ane Marie
;
Olsen, Jorn
;
Bonde, Jens Peter
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 96 no. 02 (Aug. 2011)
,
page 295-298.
Topik:
Folate
;
folic acid
;
male factor infertility
;
nutrients
;
reproduction
;
semen quality
;
sex hormones
;
vitamins
Ketersediaan
Perpustakaan FK
Nomor Panggil:
F02.K.2011.04
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Objective To examine whether maternal folic acid supplement intake during pregnancy is related to better semen quality in male offspring. Design A follow-up study. Setting Two major Danish municipalities, Aalborg and Odense. Patient(s) The study population included 347 singleton sons of mothers enrolled into the Healthy Habits for Two cohort when pregnant in 1984–87. Intervention(s) Information on maternal folic acid supplement intake during pregnancy was provided by self-administered questionnaire in the 36th week of gestation. Main Outcome Measure(s) Semen characteristics and serum concentrations of sex hormones. Result(s) The distribution of semen characteristics among sons whose mothers took folic acid supplement during pregnancy (n = 88, 25%) did not differ from the distributions among those without (n = 75, 22%) or with unknown folic acid supplement intake (n = 84, 53%). On the contrary, serum levels of FSH and LH were significantly higher in the folic acid supplement group. Conclusion(s) The hypothesis that folic acid supplement intake during pregnancy will improve semen quality in male offspring was not corroborated by a follow-up study in young Danish men.
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