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Twice-frozen embryos are no detriment to pregnancy success: a retrospective comparative study
Oleh:
Koch, Juliette
;
Costello, Michael F.
;
Chapman, Michael G.
;
Kilani, Suha
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 96 no. 01 (Jul. 2011)
,
page 58-62.
Topik:
Twice-frozen embryos
;
infertility
;
pregnancy rate
;
live birth rate
;
IVF/ICSI
Ketersediaan
Perpustakaan FK
Nomor Panggil:
F02.K.2011.04
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Objective To compare the pregnancy rates (PR) and live birth rates in once- versus twice-frozen ET treatment cycles in the same cohort of women. Design A retrospective study. Setting Fertility clinics, IVF Australia, New South Wales. Patient(s) The study population was all women who underwent thawing of twice-frozen embryos between January 2003 and May 2009. Intervention(s) Twice-frozen, twice-thawed embryos. Main Outcome Measure(s) Pregnancy and live birth rate. Result(s) There were 44 women who had 52 twice-frozen ET treatment cycles. The mean age of the women was 32 ± 4.4 years and the mean number of embryos transferred was 1.1 in both the once-frozen and twice-frozen ET treatment cycles. Twice-frozen embryos had a lower post-thaw survival rate compared with the once-frozen embryos. There was no significant difference in the clinical PR or live birth rate per ET between twice-frozen and once-frozen ETs. Conclusion(s) Twice-frozen-thawed embryos have a lower post- thaw survival rate but equivalent pregnancy and live birth rates to once-frozen embryos. Further studies are necessary to confirm our findings and to assess long-term safety outcomes.
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