Structural and Functional Neuroplasticity in Relation to Traumatic Stress  

Oleh:

Kolassa, Iris-Tatjana ; Elbert, Thomas

Jenis: Article from Journal - e-Journal
Dalam koleksi: Current Directions in Psychological Science vol. 16 no. 06 (Dec. 2007), page 321-325.
Topik: Amygdala; Hippocampus; Neuroplasticity; Posttraumatic Stress Disorder; Stress
Fulltext: 07. Structural and Functional Neuroplasticity in Relation to Traumatic Stress.pdf (135.19KB)

Isi artikel

The body’s stress response is an essential adaptive and protective mechanism to cope with threatening situations. However, chronic or traumatic stress leads to structural and functional alterations in the traumatized brain. We argue for a building-block effect: Exposure to different types of traumatic events increases the probability of developing posttraumatic stress disorder (PTSD), via incremental enlargement of a fear network. We summarize evidence of brain changes in PTSD, including recent results from research on animal models of stress-related neuroplastic remodeling, with an emphasis on structural and functional changes in the hippocampus, the amygdala, and the medial prefrontal cortex.

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