Vitamin D deficiency and anthropometric indicators of adiposity in school-age children: a prospective study  

Oleh:

Gilbert-Diamond, Diane ; Baylin, Ana ; Mora-Plazas, Mercedes ; Marin, Constanza ; Arsenault, Joanne E ; Hughes, Michael D. ; Willett, Walter C. ; Villamor, Eduardo

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The American Journal of Clinical Nutrition vol. 92 no. 06 (Dec. 2010), page 1446-1451.
Fulltext: Am J Clin Nutr-2010-Gilbert-Diamond-1446-51.pdf (78.86KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: A07.K.2010.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: Cross-sectional studies have indicated that vitamin D serostatus is inversely associated with adiposity. It is unknown whether vitamin D deficiency is a risk factor for the development of adiposity in children. Objective: We investigated the associations between vitamin D serostatus and changes in body mass index (BMI; in kg/m2), skinfold-thickness ratio (subscapular-to-triceps), waist circumference, and height in a longitudinal study in children from Bogota, Colombia. Design: We quantified plasma 25-hydroxyvitamin D [25(OH)D] concentrations in baseline samples of a randomly selected group of 479 schoolchildren aged 5–12 y and classified vitamin D status as deficient [25(OH)D concentrations <50 nmol/L], insufficient [25(OH)D concentrations =50 and <75 nmol/L], or sufficient [25(OH)D concentrations =75 nmol/L]. We measured anthropometric variables annually for a median of 30 mo. We estimated the average change in each anthropometric indicator according to baseline vitamin D status by using multivariate mixed linear regression models. Results: Vitamin D–deficient children had an adjusted 0.1/y greater change in BMI than did vitamin D–sufficient children (P for trend = 0.05). Similarly, vitamin D–deficient children had a 0.03/y (95% CI: 0.01, 0.05/y) greater change in subscapular-to-triceps skinfold-thickness ratio and a 0.8 cm/y (95% CI: 0.1, 1.6 cm/y) greater change in waist circumference than did vitamin D–sufficient children. Vitamin D deficiency was related to slower linear growth in girls (-0.6 cm/y, P = 0.04) but not in boys (0.3 cm/y, P = 0.34); however, an interaction with sex was not statistically significant. Conclusion: Vitamin D serostatus was inversely associated with the development of adiposity in school-age children.

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