From Genes to Brain to Antisocial Behavior  

Oleh:

Raine, Adrian

Jenis: Article from Journal - e-Journal
Dalam koleksi: Current Directions in Psychological Science vol. 17 no. 05 (Oct. 2008), page 323-328.
Topik: Brain Imaging; Genetics; Antisocial; Moral; Treatment
Fulltext: 06. From Genes to Brain to Antisocial Behavior.pdf (165.62KB)

Isi artikel

This review summarizes recent brain-imaging and molecular-genetic ?ndings on antisocial, violent, and psychopathic behavior. A ‘‘genes to brain to antisocial behavior’’ model hypothesizes that speci?c genes result in structural and functional brain alterations that, in turn, predispose to antisocial behavior. For instance, a common polymorphism in the monoamine oxidase A (MAOA) gene has been associated with both antisocial behavior and also reductions in the volume of the amygdala and orbitofrontal (ventral prefrontal) cortex—brain structures that are found to be compromised in antisocial individuals. Here I highlight key brain regions implicated in antisocial behavior, with an emphasis on the prefrontal cortex, along with ways these areas give expression to risk factors for antisocial behavior. Environmental in?uences may alter gene expression to trigger the cascade of events that translate genes into antisocial behavior. Neuroethical considerations include how responsibility and punishment should be determined given the hypothesis that neural circuits underlying morality are compromised in antisocial individuals.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali