Anda belum login :: 23 Nov 2024 09:51 WIB
Detail
ArtikelThe Amount of Surface HLA-I on T Lymphocytes Decreases in Breast Infiltrating Ductal Carcinoma Patients  
Oleh: S, Zhao ; X, Yang ; N, Lu ; Y, Zhang ; X, Li ; Y, Li ; Y, Zhou ; F, Wan ; X, Zou
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 39 no. 02 (Mar. 2011), page 508-513.
Topik: Breast Infiltrating Ductal Carcinoma; Human Leucocyte Antigen Class I; T Lymphocytes; Immune Escape
Fulltext: 1612.pdf (94.98KB)
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: J11.K
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
    Lihat Detail Induk
Isi artikelHuman leucocyte antigen class I (HLA-I), which includes HLA-A, -B and -C, is an essential immune factor participating in the antitumour immune response. The changes in HLA-I expression in peripheral blood T lymphocytes in cancer patients have yet to be defined. This study examined the expression of HLA-I on CD4+ and CD8+ T lymphocytes in female patients with stage I – IV breast infiltrating ductal carcinoma, benign breast tumour diseases (mammary intraductal papilloma or breast fibroadenoma), and in healthy controls. HLA-I was down-regulated on CD4+ T lymphocytes from patients with stage III and IV cancer, and on CD8+ T lymphocytes in patients with stage I – IV cancer compared with healthy controls. HLA-I expression in T lymphocytes may contribute towards immune-balance disorders in tumour patients.
Opini AndaKlik untuk menuliskan opini Anda tentang koleksi ini!

Kembali
design
 
Process time: 0.03125 second(s)