Evaluation of Diffusion-weighted Magnetic Resonance Imaging and Contrast-enhanced Harmonic Ultrasonography in Detection and Location of Prostate Transition-zone Cancer  

Oleh:

R, Wang ; J-J, Chen ; Y-C, Zhou ; M-M, Huang ; X-R, Zhang ; H-D, Miao

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 39 no. 01 (Mar. 2011), page 256-266.
Topik: PROSTATE CANCER; Prostate Cancer; Diffusion-Weighted Magnetic Resonance Imaging; Contrast-Enhanced Harmonic Ultrasonography; Transition Zone
Fulltext: 1582.pdf (174.44KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: J11.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

,3,4Department of Ultrasound in Medicine, The 6th People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China; 2Department of Children’s Care and Health, Shanghai Children’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China; 5Department of Urology, The 6th People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China; 6Department of Radiology, Huashan Hospital Affiliated to Fudan University, Shanghai, China This retrospective study was designed to evaluate the value of contrast-enhanced harmonic ultrasonography (CEHU), diffusion-weighted magnetic resonance imaging (DW-MRI) and CEHU plus DW-MRI for the diagnosis of prostate transition-zone (TZ) cancer. In total, 31 TZ cancers in 28 patients and 25 peripheral zone (PZ) cancers in 21 patients without a TZ cancer were evaluated. All patients underwent DW-MRI and CEHU followed by radical prostatectomy. Predictors for the diagnosis of prostate cancer were evaluated in three protocols (CEHU, DW-MRI, CEHU plus DWMRI). Statistical analysis of the differences between these protocols and receiver operating characteristic (ROC) curve analysis were carried out. CEHU plus DWMRI had a significantly higher sensitivity, accuracy and negative-predictive value (90.3%, 73.2% and 81.3%, respectively) for TZ cancer than either method alone. The area under the ROC curve values were 0.659, 0.679 and 0.712 for CEHU, DW-MRI, and CEHU plus DW-MRI, respectively. In conclusion, CEHU plus DW-MRI might be a useful protocol for the detection and location of TZ cancer.

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