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Prevalensi Acinetobacter baumannii Karbapenemase Positif dengan Metode Blue Carba Test di Rumah Sakit Atma Jaya, Jakarta Tahun 2014-2017
Bibliografi
Author:
ANGELINE, DIANITA
;
Tjoa, Enty
(Advisor);
Sahiratmadja, Edhyana Kusumastuti
(Examiner)
Topik:
NOSOCOMIAL INFECTIONS
;
Acinetobacter baumannii
;
Blue Carba Test
;
Carbapenemase
;
Karbapenemase
Bahasa:
(ID )
Penerbit:
Fakultas Kedokteran Unika Atma Jaya
Tempat Terbit:
Jakarta Utara
Tahun Terbit:
2018
Jenis:
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext:
KTI Dianita Angeline (2014060150).pdf
(20.34MB;
5 download
)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
KTI-FK- 1384
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Abstract
Background. Acinetobacter baumannii is a gram negative bacteria frequently found in hospital and accounts for oportunistic nosocomial infection. Reports from various
parts of the world have suggested that the incidence of A. baumannii infections is increasing significantly and is followed by resistance towards antibiotics. This resistance is mainly caused by the production of carbapenemase enzyme that can hydrolyze beta-lactam ring in antibiotics such as penicillins, carbapenems, and monobactams. This study aims to investigate the carbapenemase producer among carbapenem resistant A. baumannii using Blue Carba Test.
Method. Carbapenem resistant A. baumannii isolates in this observational descriptive study were acquired from clinical specimens in Atma Jaya Hospital taken from January 2014 – September 2017 which were stored in Microbiology Laboratorium of Atma Jaya's Faculty of Medicine. Antibiotic susceptibility test data were taken from WHONET 5.3. program. Thirty six isolates were successfully revived and tested for carbapenemase production using Blue Carba Test.
Results. From a total of 142 isolates collected from clinical specimens, 51,4% (73/142) were resistant to carbapenem. All isolates (n=36) tested for blue carba test
were found to be carbapenemase producer.
Conclusion. The prevalence of carbapenemase producer among carbapenem resistant Acinetobacter baumannii is 100% (36/36). This finding may aid clinicians in selecting
antibiotic for A. baumannii infection.
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