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Perbandingan Efektivitas antara Kombinasi Pemeriksaan Laboratorium: Rasio Neutrofil Limfosit, Protein C-Reaktif, Hitung Leukosit pada Pasien Apendisitis Akut
Bibliografi
Author:
KRISTIANTI, CLARA DEVINA
;
Soeselo, Daniel Ardian
(Advisor);
Lembar, Stefanus
(Examiner)
Topik:
ACUTE APPENDICITIS
;
neutrophyl-limphocyte ratio
;
c-reactive protein
;
leukocyte count
;
acute appendicitis
;
asio neutrofil-limfosit
;
protein C-reaktif
;
hitung leukosit
;
apendisitis akut
Bahasa:
(ID )
Penerbit:
Fakultas Kedokteran Unika Atma Jaya
Tempat Terbit:
Jakarta Utara
Tahun Terbit:
2018
Jenis:
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext:
KTI Clara Devina Kristianti (2014060041).pdf
(1.97MB;
18 download
)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
KTI-FK- 1383
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Abstract
Background: Acute appendicitis is an acute inflammation of appendix vermiformis which duration is no longer than 48 hours and needs immediate surgery to prevent any dangerous complications. Diagnosing this disease becomes difficult because of the uncharactherized signs and symptoms in patients. There are no inflammation biomarkers which has high sensitivity and spesificity towards acute appendicitis.
Objective: To investigate the effectivity of laboratorium examination combination in diagnosing patients with acute appendicitis.
Methods: This study is an analityc observasional with a cross sectional approach, which was conducted among 52 patients with suspected acute appendicitis.
Results: Sensitivity and specificity of the combination of neutrophyl-lymphocyte ratio and c-reactive protein is 50,00% and 64,30%. For neutrophyl-lymphocyte ratio and leukocyte count, it has 45,80% sensitivity and 60,70% specificity. In test combinations of c-reactive protein - leukocyte count and all three biomarkers: neutrophyl-limphocyte ratio; c-reactive protein;and leukocyte count, the sensitivity is 33,33% and 75% specificity.
Conclusion: The most effective examination combination to diagnose acute appendicitis is the combination of neutrophyl-lymphocyte ratio and c-reactive protein.
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