Ultrasound-guided high-intensity focused ultrasound ablation for adenomyosis: the clinical experience of a single center  

Oleh:

Min, Zhou ; Jin-Yun, Chen ; Liang-Dan, Tang ; Wen-Zhi, Chen ; Zhi-Biao, Wang

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 95 no. 03 (Mar. 2011), page 900-905.
Topik: ULTRASOUND; High-intensity focused ultrasound; uterus; adenomyosis; ultrasound ablation; thermal ablation

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2011.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To assess the midterm outcomes after ultrasound-guided high-intensity focused ultrasound (HIFU) ablation in treatment of patients with symptomatic adenomyosis. Design A prospective clinical trial. Setting University teaching hospital. Patient(s) Seventy-eight patients with symptomatic adenomyosis. Intervention(s) A single treatment session of ultrasound-guided HIFU ablation for adenomyosis. Main Outcome Measure(s) Dysmenorrhea and menorrhagia scores and the incidence of complications. Result(s) In all 78 patients, 84.6% tolerated the treatment procedure well with pain scores between 0 and 4. Treatment was terminated in only one patient because of increased blood pressure persistently. Sixty-nine patients have finished at least an 18-month follow-up; the mean follow-up time was 24.2 months. Nonperfused regions in lesions were observed in 60 (87.0%) patients on the enhanced magnetic resonance imaging scans. Scores for menorrhea and dysmenorrhea decreased. Clinical effectiveness of the treatment was observed in 62 women (89.9%) with varying degrees of symptomatic relief of dysmenorrhea. Eight patients had relapses. Twenty-two patients (28.6%) had 27 complications. Of these, four had two or more complications. Twenty-three events (85.1%) did not need medical intervention (Society of Interventional Radiology class A). No serious complications including death or major permanent injuries were observed. Conclusion(s) Ultrasound-guided HIFU ablation may be a safe and effective noninvasive alternative in the treatment of symptomatic adenomyosis.

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