Effectiveness of misoprostol for office hysteroscopy without anesthesia in infertile patients  

Oleh:

Sordia-Hernández, Luis Humberto ; Rosales-Tristan, Elizabeth ; Vazquez-Mendez, Juanita ; Merino, Martha ; Iglesias, Jose Luis ; Garza-Leal, Jose Gerardo

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 95 no. 02 (Feb. 2011), page 759-761.
Topik: REPRODUCTIVE SURGERY; Office hysteroscopy; misoprostol; oral; vaginal

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2011.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To evaluate and compare the effectiveness of oral and vaginal misoprostol versus placebo to facilitate office hysteroscopy without anesthesia during infertile diagnostic evaluation. Design Randomized, prospective trial. Setting Patients scheduled for diagnostic office hysteroscopy at a university hospital. Patient(s) Seventy-five infertile patients scheduled for diagnostic office hysteroscopy. Intervention(s) Patients were divided into three groups: group A received oral misoprostol 600 µg; group B, vaginal misoprostol 400 µg; and group C, oral placebo. Main Outcome Measure(s) Pain, evaluated by visual analogue scale, and surgical time were recorded and compared. Statistical analysis was done using Student's t-test. Result(s) Pain was low in the vaginal misoprostol group. Mean visual analogue scale in the oral misoprostol group was 6.04 ± 1.5; in the vaginal misoprostol group 2.85 ± 1.2; and in the placebo group 7.50 ± 1.5. Procedural time for office hysteroscopy was shorter in the vaginal misoprostol group (2.7 ± 1.0 minutes) compared with group A (5.5 ± 1.1 minutes) and group C (6.3 ± 3.8 minutes). Conclusion(s) Vaginal misoprostol, 400 µg, administered the day before office hysteroscopy considerably reduces pain and the time needed for hysteroscopy. This simple strategy may facilitate office hysteroscopy during an infertility work-up.

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