Considering Race/Ethnicity and Socio-economic Status in Randomized Controlled Trials. A Commentary on Frampton et al.'s Systematic Review Generalizing Trial Findings and Tackling Health Disparities in Asthma Research  

Oleh:

Kreatsoulas, Catherine ; Anand, Sonia

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Social Science & Medicine (www.elsevier.com/locate/sosscimed) vol. 69 no. 8 (Oct. 2009), page 1155-1156.
Topik: Race/Ethnicity; Gender; Health Disparities; Subgroup Analysis; Randomized Controlled Trials

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: SS53 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The selection of the ideal "population" to be enrolled in randomized clinical trials (RCTs) has been debated over the past two decades. Some advocate for the selection of a "homogenous" population, for example white males between 30 and 50 years of age, while others advocate for a more representative sampling of the "at risk" population (Peto, Collins, & Gray, 1995; Yusuf, Collins, & Peto, 1984). The latter group believe that heterogenity within the trial population is an asset, for if the trial is large enough, the main results of the RCT are valid, and generalizability is increased. Given this debate in trial design, it is not surprising that current trials reflect both approaches, and consequently the generalizability of trial results remains a hotly debated issue.

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