Are there ethnic differences in pregnancy rates in African-American versus white women undergoing frozen blastocyst transfers?  

Oleh:

Csokmay, John M. ; Hill, Micah J. ; Maguire, Marcy ; Payson, Mark D. ; Fujimoto, Victor Y.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 95 no. 01 (Jan. 2011), page 89-93.
Topik: Ethnicity; racial; disparities; live birth rate; infertility; IVF; ART

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2011.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To determine whether frozen-thawed blastocyst transfer pregnancy rates (PR) are lower in African-American compared with white women. Design Retrospective review of frozen blastocyst cycles. Setting University-based assisted reproductive technology (ART) program. Patient(s) All patients who underwent a frozen blastocyst transfer between 2003 and 2008. Intervention None. Main Outcome Measure(s) Live birth rate. Result(s) One hundred sixty-nine patients underwent transfer of a frozen-thawed blastocyst. African-American women had a higher incidence of leiomyoma (40% vs. 10%) and tubal and uterine factor infertility. There was no difference in the live birth rate for African-American patients (28.0%) compared with white patients (30.2%). Of the patients who underwent a frozen-thawed blastocyst transfer, 58% (n = 98) had their fresh, autologous IVF cycle, which produced the cryopreserved blastocyst, at Walter Reed Medical Center. A higher peak serum E2 level was noted in African-American patients (5,355 pg/mL) compared with white patients (4,541 pg/mL). During the fresh cycle, the live birth rates between African-American and white patients were significantly different at 16.7% versus 39.7%, respectively. Conclusion(s) Live birth rates after frozen blastocyst transfer are not different between African-American and white women despite a fourfold higher incidence of leiomyomas in African-American women.

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