Perubahan Amplitudo Kontraksi Otot Uterus Tikus Akibat Pemberian Rumput Fatimah (Anastatica Hierochuntica L)  

Oleh:

Nani, Desiyani

Jenis: Article from Journal - ilmiah nasional
Dalam koleksi: Mandala of Health (A Scientific Journal) vol. 04 no. 01 (Jan. 2010), page 47-52.
Topik: Fatimah's grass (Anastatica hierochuntica L); the quality of uterine smooth muscle contraction; amplitude; estrous stage; oxytocin; estrogen

Ketersediaan

Perpustakaan FK Nomor Panggil: M50.K.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The amplitude of contraction is one of the mechanical activities of uterine smooth muscle contractions Recording was done without and with 0.01 IU oxytocin stimulation entered into organ bath within uterine smooth muscle strips. The aim of this research was to investigate the effect of water soaked of fatimah grass (Anastatica hierochuntica L) on the amplitude of uterine smooth muscle contractions of rattus nontegicus Sprague Dawley at the estrous phase both in without and with 0,0I IU oxytocin stimulation This research was laboratory experimental with post test only control group design. The samples were 40 uterine smooth muscle strips rattus norvegicus Sprague dawley 10-14 weeks, 150 - 250 gr weight, on the estrous stages. The rats were divided into 5 groups. Control group was treatment by vehicle of solution (water), equivalent group was treatment by estradiol, and the others were treatment by fatimah's grass 10 gr, 20 gr, and 40 gr that soaked into 350 cc hot water (70°C) during 12 hours. Twenty hours after treatment, rats were killed, and than uterine smooth muscle was removed and connected to chymograph to record the contractions. The data was analyzed by oneway Anova and the results shaved there was significant dgerences in amplitude @=0,004) between treatment groups and control or equivalent groups on the uterine smooth muscle strips without oxytocin stimulation. And then paired t-test results showed that there were no significant diferences between amplitudes without and with 0,01 IU oxytocin stimulation it could be concluded that the water soaked of fatimah grass (Anastatica hierochuntica L) couldn't increased the amplitude of uterine smooth muscle contractions of rattus norvegicus Sprague Dawley at the estrous phase

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