Sepsis  

Oleh:

Cohen, Jonathan

Jenis: Article from Bulletin/Magazine - ilmiah internasional
Dalam koleksi: Medical Progress vol. 38 no. 02 (Feb. 2011), page 85.
Topik: infectious diseases

Ketersediaan

Perpustakaan FK Nomor Panggil: M36.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Sepsis is the systemic response to infection, usually caused by bacterial infections ( both Gram positive and Gram negative). It is a common condition with an overall mortality of about 30%, even when treated apropriately. It can be difficult to recognize at the early stages. Sepsis and septic shock are characterizied by multiorgan failure, which is caused by a dysregulated immune response to the infection. Effective management depends on early initiation of treatment. All patients should receive oxygen and fluids. Most will require vasopressor. Pus should be drained. Antibiotics need to be given as quickly as possible and will usually be broad-spectrum, bearing in mind the likely causative organisms and the possibility of antimicrobial resistance. Patients satisfying the NICE criteria should be given drotrecogin alfa (activated).

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