Detail CD8+ T-cell responses in acute hepatitis C virus infection (from Frontiers in Immunology: Reviews Article 2014, 5 (266), 1-7) Bibliografi Author: Sung, Pil Soo ; Racanelli, Vito ; Shin, Eui-Cheol Topik: Hepatitis C virus; Acute infection; Outcome; CD8C T-cell; Function; D seminar Bahasa: (EN )     Tahun Terbit: 2014     Jenis: Article - diterbitkan di jurnal ilmiah internasional Fulltext: fimmu-05-00266.pdf (1.03MB; 0 download) [Informasi yang berkaitan dengan koleksi ini di internet] Abstract Hepatitis C virus (HCV) infects approximately 170 million people worldwide and is a major cause of life-threatening liver diseases such as liver cirrhosis and hepatocellular carcinoma. Acute HCV infection often progresses to chronic persistent infection, although some patients recover spontaneously.The divergent outcomes of acute HCV infection are known to be determined by differences in virus-specific T-cell responses among patients. Of the two major T-cell subsets, CD8C T-cells are known to be the key effector cells that control viral infections via cytolytic activity and cytokine secretion. Herein, we review various aspects of HCV-specific CD8C T-cell responses in acute HCV infection. In particular, we focus on timing of CD8C T-cell responses, relationship between CD8C T-cell responses and outcomes of acute HCV infection, receptor expression on CD8C T-cells, breadth of CD8C T-cell responses, and viral mutations. [d seminar] Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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