Daur Sel dan Apoptosis: Tinjauan Biomolekular Pada Sel Normal dan Kanker  

Oleh:

Purwaningsih, Endang

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Widya: Majalah Ilmiah vol. 26 no. 292 (Jan. 2010), page 17-23.
Topik: Daur Sel; Apoptosis; Biomolekular; Sel Normal dan Kanker.

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: MM47.29 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Cell growth and development requires cell proliferation through a controlled mechanism. If cell exits from normal mechanism pathway, it will form cancer cell having ability to continuously proliferate. The objective of this article is to discuss the cell growth and development in detail. The data collected from library research and analyzed descriptively. The conclusions are that in normal process the cell will experience death which functions to improve cell and release damaged cell. For proliferating, the cell enters the cycle where the cell will be multiplicated which is similar to somatic cell and involves cell growth component and arranges division to divide into two new cells. Normally cell cycle covers to conditions, namely proliferative/mitosis/M phase, quiescent/Go phase and permanently does not divide. Dividing cancer cell is located in phase without GO, namely G1, S (synthesis), G2 and M (mitosis). Cell cycle regulation mechanism requires some genes and proteins such as oncogen, suppressor genes, cyclin, CDKS, CKIs; while apoptosis process requires proteins such as p53, caspase, Bcl-2, Apaf. Apoptosis process can be induced by intrinsic and extrinsic process

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