Background: The ability to remember is a useful thing in our life and to do so, one would need a good memory. Spatial memory is a type of memory that uses one’s saved information to determine one’s position and movement (as a navigation system). There are so many theories about the cause of memory impairment, and that piques researcher’s interest because in those theories, the causes are commonly found in one’s daily life. In this opportunity, the researcher chose to seek the effect of swimming as an activity that could affect the cause of memory impairment on C57BL/6 mice’s spatial memory function.
Objectives: To determine the effect of swimming on C57BL/6 mice’s spatial memory.
Method: This is an animal trial research using two groups as subjects, which are the control and swimming group. Both groups will be trained using Morris Water Maze (MWM) for five days with four trials per day for each mice, and then the MWM test will be done on the next day (1st day) and after a complete three weeks of intervention (22nd day). The swimming group will be given swimming intervention for 60 minutes/session, with 5 sessions/week for 3 weeks.
Result and Conclusion: No significant difference found on escape latency of swimming group (p = 0,326; p = 0,05) compared to control group (p = 0,851; p = 0,05). There were also no significant difference found on path length of swimming group (p = 0,875; p = 0,05) compared to control group (p = 0121; p = 0,05), so it can be concluded that swimming for 60 minutes/session, with 5 session/week for 3 weeks has no significant effect on C57BL/6 mice’s spatial memory. |