Progestogen treatments for cycle management in a sheep model of assisted conception affect the growth patterns, the expression of luteinizing hormone receptors, and the progesterone secretion of induced corpora lutea  

Oleh:

Letelier, Claudia ; Garcia-Fernandez, Rosa Ana ; Contreras-Solis, Ignacio

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 93 no. 04 (Mar. 2010), page 1308-1315.
Topik: Progestogens; pituitary function; luteal function; LH receptors; sheep

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To determine, in a sheep model, the effect of a short-term progestative treatment on growth dynamics and functionality of induced corpora lutea. Design Observational, model study. Setting Public university. Patient(s) Sixty adult female sheep. Intervention(s) Synchronization and induction of ovulation with progestogens and prostaglandin analogues; ovarian ultrasonography, blood sampling, and ovariectomy. Main Outcome Measure(s) Determination of pituitary function and morphologic characteristics, expression of luteinizing hormone (LH) receptors, and progesterone secretion of corpora lutea. Result(s) The use of progestative pretreatments for assisted conception affect the growth patterns, the expression of LH receptors, and the progesterone secretion of induced corpora lutea. Conclusion(s) The current study indicates, in a sheep model, the existence of deleterious effects from progestogens on functionality of induced corpora lutea.

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