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Kesesuaian Diagnosis Klinis Gastroenteritis Akut Bakterial dengan Hasil Pemeriksaan Biakan Feses Pasien Bangsal Anak RSAJ
Bibliografi
Author:
Ardianto, Christian
;
Surjono, Edward
(Advisor);
Tjoa, Enty
(Advisor);
Nadesul, Belinda
(Examiner);
Dewi, Rita
(Ketua Sidang)
Topik:
GASTROENTERITIS
;
Bacterial acute gastroenteritis
;
Clinical diagnosis
;
Fecal Culture
;
Agreement
;
Gastroenteritis Akut Bakterial
;
Diagnosis Klinis
;
Biakan Feses
;
Kesesuaian
Bahasa:
(ID )
Penerbit:
Fakultas Kedokteran Unika Atma Jaya
Tempat Terbit:
Jakarta Utara
Tahun Terbit:
2016
Jenis:
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext:
KTI Christian Ardianto (2013060014).pdf
(2.34MB;
30 download
)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
KTI-FK-1105
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Abstract
Background. Incidence of Acute Gastroenteritis in Indonesia is moderately high and is known as the highest cause of death on newborn and child. Disagreement of clinical and laboratory methods for diagnosing must be noted for the increasing resistant strain bacterias and the difficulty of treatment in superinfection. Laboratory method to determine the causative agent is not a routine test in majority of the children suffered of acute gastroenteritis and the effort of clinician to identify the causative agent has not yet optimal in the case of acute gastroenteritis. Agreement and accuracy of clinical diagnosis and laboratory methods are important to reduce the inappropriate use of antibiotics and missed positive of bacterial acute gastroenteritis.
Objectives. The aim of this research is to determine sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio, accuracy, and agreement of clinical and laboratory methods for diagnosing bacterial acute gastroenteritis.
Methodology. This agreement comparative study was conducted in July 2016 until May 2016 using the whole sampling method. This study was carried out in Pediatric Ward at Atma Jaya Hospital and Microbiology Laboratory at Atma Jaya School of Medicine. Clinical diagnosis was observed through medical records and the laboratory diagnosis was done by using isolation and identification standard in Microbiology Laboratory at Atma Jaya School of Medicine. Data was analyzed by Cohen’s Kappa to determine the agreement with 95% confidence level, precicion 20%, true positive prediction value 50%, and minimum kappa value 90%.
Results and Conclusions. Clinical diagnosis of bacterial acute gastroenteritis has sensitivity of 45%, specificity of 60%, positive predictive value of 82%, negative predictive value of 21%, positive likelihood ratio of 1.125, negative likelihood ratio of 0.916, accuracy of 48%, and kappa value of 3% shows only slight agreement with laboratory methods.
Suggestion. The suggestion is to have more sample so that the data can be more representative. Measuring sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio, accuracy, and kappa value for each symptom and sign of bacterial acute gastroenteritis is important input to help in making the algorithm that combining between clinical diagnosis and laboratory methods. Similar research should be conducted to other infection disease considering the increasing numbers of resistant strain bacterias.
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