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BukuPerbandingan Efektifitas Okra (Abelmoschus esculentus) dan Kembang Sepatu (Hibiscus rosa sinsensis) Terhadap Kadar Gula Darah Tikus yang Diinduksi dengan Aloksan
Bibliografi
Author: WIJAYA, FRISKA WILDA ; Susanto, Karim (Advisor); Lembar, Stefanus (Examiner)
Topik: HERBAL MEDICINE; Okra; Hibiscus; Blood Glucose; Sprague Dawley Rats; Kembang Sepatu; Glukosa darah; Tikus Sprague Dawley
Bahasa: (ID )    
Penerbit: Fakultas Kedokteran Unika Atma Jaya     Tempat Terbit: Jakarta Utara    Tahun Terbit: 2016    
Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext: KTI Friska Wilda Wijaya 2013060137.pdf (1.73MB; 42 download)
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: KTI-FK-1030
    • Non-tandon: tidak ada
    • Tandon: 1
 Lihat Detail Induk
Abstract
Background : The popularity of medicinal plants are increasing due to their minimal side effect. Abelmoschus esculentus and Hibiscus rosa sinensis is known to have many benefits. One of its benefits is in reducing blood sugar levels because of their flavonoid content. This study aims to look at the effects of okra and hibiscus in reducing blood sugar levels and whether there are differences in effectiveness between the two plants.
Methods : This study was an experimental study with analytic studies. The study was conducted over 18 days using 30 rats types Sprague Dawley and were divided into 6 groups, negative control (1), a positive control (2), intervention okra 1 (3), intervention okra 2 (4), intervention hibiscus 1 (5 ), intervention hibiscus 2 (6). Each intervention group consisted of 5 rats that were diabetically induced with alloxan and was given intervention at a dose of 100 and 200 mg/kgbodyweight /day. Blood glucose was tested with a glucometer before induction, 3 days after induction, and every 2 days after the intervention for 12 days..
Result : Based on the data acquired, significant reduction of blood glucose levels were found in each intervention groups. The P values of each intervention groups paired T-test results are below 0,05 between pre-intervention and post-intervention. However, with one way ANOVA and post-hoc Bonferroni, P values were above 0,05. Hence, there is no effective differences between administering okra and hibiscus in 100 mg/kgbodyweight dan 200 mg/kgbodyweight dose.
Conclusion : Administering okra and hibiscus shows statistically proven reduction in blood glucose levels on diabetic rats. But, there are no effective differences between administering okra and administering hibiscus.
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