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Pengaruh Pemberian Cairan Nepenthes rafflesiana Sebagai Antifungi Terhadap Pertumbuhan Candida glabrata
Bibliografi
Author:
BUDIMAN, YURI FITRI
;
Yolanda, Hanna
(Advisor);
Makimian, Robby
(Examiner)
Topik:
ANTIFUNGAL
;
Candida glabrata
;
Nepenthes rafflesiana
;
Antifungal
;
Antifungi
Bahasa:
(ID )
Penerbit:
Fakultas Kedokteran Unika Atma Jaya
Tempat Terbit:
Jakarta Utara
Tahun Terbit:
2015
Jenis:
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext:
KTI Yuri Fitri Budiman.pdf
(2.23MB;
4 download
)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
KTI-FK-987
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Abstract
Candidosis is one of world’s health problems shown by an increase of number of cases by 207%. One of the causes of candidosis is Candida glabrata. C. glabrata is a non-Candida albicans species which is resistant to several kinds of antifungal agents, thus C.glabrata is called as azole-resistant yeast. Nepenthes rafflesiana is a carnivore plant that has a pitcher containing fluid suspected to have an antifungal effect.
Goal. The purpose of this study is to know the effect of N. rafflesiana’s fluid from fresh-opened and closed pitcher in several concentrations, so that it can be used as an alternative therapy to candidosis.
Method. This is a laboratory experimental study using two methods, disk diffusion test and macrodilution test.
Result. The disk diffusion test result shows that there is no inhibition zone was formed by both types of N. rafflesiana’s fluid. However, macrodilution test result shows a decrease in colonization growth of C. glabrata by N. rafflesiana’s fluid from either fresh-opened or closed pitcher in 20%, 35%, 50% concentrations.
Conclusion. This indicates that N. rafflesiana’s fluid has an antifungal effect against Candida glabrata’s growth.
Suggestion. Molecular research of N. rafflsiana’s fluid from fresh-opened and closed pitcher.
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