Rate of severe ovarian damage following surgery for endometriomas  

Oleh:

Benaglia, Laura ; Somigliana, Edgardo ; Vighi, Valentina

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Human Reproduction vol. 25 no. 03 (Mar. 2010), page 678-682.
Topik: endometriosis; endometrioma; ovarian failure; surgery; IVF

Ketersediaan

Perpustakaan FK Nomor Panggil: H07.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

BACKGROUND There is growing and consistent evidence showing that ovarian reserve is affected following surgical excision of ovarian endometriomas. Of particular concern is the risk of severe ovarian damage leading to unresponsiveness to ovarian hyperstimulation. In this study, we aimed to determine the rate of this complication. METHODS Ninety-three women underwent surgery for monolateral endometriomas were recruited. Patients who underwent IVF were selected and, in all cases, follicular growth was monitored by serial transvaginal ultrasonography. The main outcome measure was the rate of ovaries remaining silent when stimulated after surgery for endometriomas. RESULTS Absence of follicular growth was observed in 12 operated ovaries although this event never occurred in the contralateral gonad (P < 0.001). The frequency (95% confidence interval) of severe ovarian damage following surgery was 13% (7–21%). CONCLUSIONS Severe ovarian damage, occurring in gonads operated on for ovarian endometriomas, is not a rare event.

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