Gene Doping: The Hype and the Harm  

Oleh:

McKanna, Trudy A. ; Toriello, Helga V.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 57 no. 03 (Jun. 2010), page 719-727.
Topik: Gene therapy; Mutations; Detection; Polymorphisms; Athletic performance

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.2010.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

“Gene doping” is the term used to describe the potential abuse of gene therapy as a performance-enhancing agent. Gene doping would apply the techniques used in gene therapy to provide altered expression of genes that would promote physical superiority. For example, insulin-like growth factor 1 (IGF-1) is a primary target for growth hormone; overexpression of IGF-1 can lead to increased muscle mass and power. Although gene doping is still largely theoretical, its implications for sports, health, ethics, and medical genetics are significant.

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