Background: Infectious diseases still an important health problem in the world. High rates of bacterial resistance towards various antimicrobials, especially Grampositive
bacteria make the patterns of bacteria and its sensitivity an important thing to have at the level of local institutions to be used as a guide to antimicrobial therapy.
Methods: Clinical specimens taken from Atma Jaya Hospital throughout 2014. Susceptibility testing of bacteria using the Kirby-Bauer disc diffusion. Data sensitivity testing results processed using the program WHONET 5.6.
Results: In the span of one year, there are 152 isolates of Gram-positive bacteria. Most isolates are Staphylococcus epidermidis (n = 58), Staphylococcus aureus ss. aureus (n = 38), and Streptococcus viridans alpha-hem. (n = 25). Clinical specimens with the highest growth of Gram-positive bacteria are blood (n = 47), pus (n = 44), sputum (n = 28), and urine (n = 21). Antimicrobials with the highest sensitivity to Gram-positive bacteria are linezolid (89.7%), followed by vancomycin (87.1%), nitrofurantoin (84.2%), and ampicillin - sulbactam (82%). Antimicrobial with the highest resistance is aztreonam (100%), followed by nalidixic acid (90.6%) and
ampicillin (77.9%). Selection of antimicrobial for therapy is done by considering the data,above, the location of the source of infection, the availability of antimicrobials, etc.
Conclusion: Gram positive bacteria with the most isolates at Atma Jaya Hospital was Staphylococcus epidermidis. Antimicrobial sensitivity patterns vary widely, with the highest sensitivity results against Gram-positive bacteria is linezolid, vancomycin, nitrofurantoin and ampicillin - sulbactam. |