Detail Ekspresi T-Antigen JVC pada Adenoma Polip Kolon Displasia Ringan dan Berat di Laboratorium Patologi Anatomi FK Unika Atma Jaya/RS Atma Jaya Selama 5 Tahun (2009-2014) Bibliografi Author: HALIM, ANGELINA ; Harjanti, Dyonesia Ary (Advisor); CYPRIANUS MURTONO (Examiner) Topik: COLON DISEASE; colon adenomatous polyp; JCV; T-Antigen; adenoma polip kolon Bahasa: (ID )     Penerbit: Fakultas Kedokteran Unika Atma Jaya     Tempat Terbit: Jakarta Utara    Tahun Terbit: 2015     Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK) Fulltext: KTI Angelina Halim.pdf (1.49MB; 12 download) Ketersediaan Perpustakaan FK Nomor Panggil: KTI-FK-808 Non-tandon: tidak ada Tandon: 1  Lihat Detail Induk Abstract Background. Infection of JCV was often associated with pre-malignant lesion. Only few researches which detect expression of JCV in colon adenomatous polyp, including in Indonesia. The goal of this research was to detect the expression of JCV T-Antigen on mild and severe dysplasia of the colon adenomatous polyp at Anatomic Pathology Laboratory, School of Medicine Atma Jaya Catholic University of Indonesia/ Atma Jaya Hospital, Jakarta. Method. Analytic descriptive, cross-sectional study, all of the samples’ paraffin blocks were taken from colon adenomatous polyp with all degrees of dysplasia for 5 years (2009-2014). These samples would be reviewed from the HE slides to determine the histopathological diagnosis and the degree of the dysplasia. Immunohistochemistry staining with monoclonal antibody anti SV40-T-Ag would be used to detect expression of JCV T-Ag. Result. There were 7 samples of colon adenomatous polyp, 4 (57.1%) samples were mild dysplasia and 3 (42.8%) samples were severe dysplasia. Positive expression of JCV T-Ag was detected in 1 (14%) mild dysplasia of colon adenomatous polyp. Amount of 6 (86%) samples of mild and severe dysplasia of colon adenomatous polyp expressed negative JCV T-Ag. Data analysis result of JCV T-Ag expression in mild and severe dysplasia of colon adenomatous polyp using Fisher’s Exact Test was p > 0.05. Conclusion. There was no difference of JCV T-Ag expression between mild and severe dysplasia of colon adenomatous polyp. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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