Pengaruh Air Perasan Daun Cincau Hijau (Cycle barbata Miers) terhadap Konsentrasi HCI Lambung  

Oleh:

Djaman, Qathrunnada

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Sains Medika (Jurnal Kedokteran dan Kesehatan) vol. 01 no. 02 (Jul. 2009), page 140-147.
Topik: ASA; cincau hijau leaves; gastric acid

Ketersediaan

Perpustakaan FK Nomor Panggil: S11.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: Non steroidal antiinflammatory drugs such as Acetylsalicylic acid (ASA) have been largely used. Its adverse reactions include superficial gastric erotion that result in peptic ulcer. The cincau hijau leaves have long been used to relieve the digestive disorder. This study was conducted to verify the effect of cincau hijau leaves aqueous (Cyclea barbata Miers) on gastric acid concentration. Design and method: This experimental study used the post test only control group design. Thirty white male Wistar rats of 12 week old, 150-200 gram of body weight were randomly devided into five groups of six. The five groups were, administered orally with Acetylsalicylic acid 90 mg, Acetylsalicylic acid 90 mg + Sucralfat 72 mg, Acetylsalicylic acid 90 mg + cincau hijau 1,35 gram, Acetylsalicylic acid 90 mg + cincau hijau 2,70 gram, Acetylsalicylic acid 90 mg + cincau hijau 5,40 gram, respectively, They were fed on ad libitum for seven days. At the eighth day, the rats were fasted for 12 hours before terminated. The concentration of HCL was tested using Argentometry titration. The non parametric test of Kruskal-Wallis and Mann-Whitney were applied. Result: No significant different in gastric acid concentration among the treated groups (p 0.449 > 0,05), Conclusion: Cincau hijau leaves aqueous does not effect on the Acetylsalicylic acid-induced gastric acid

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