Sensitivitas dan Spesifisitas Pemeriksaan Imunokromatografi Tuberkulosis Dibandingkan dengan Kultur Lowenstein-Jensen  

Oleh:

Jannah, Della ; Rahmawati, Indah ; Rujito, Lantip

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Sains Medika (Jurnal Kedokteran dan Kesehatan) vol. 01 no. 02 (Jul. 2009), page 106-114.
Topik: culture of M. tuberculosis; diagnostic test; Immunochromatographic tuberculosis

Ketersediaan

Perpustakaan FK Nomor Panggil: S11.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: Tuberculosis remains major cause of morbidity and mortality in the world. Approximately one third of the world's population is infected with Mycobacterium tuberculosis, and it is estimated that 8 million new cases occur each year. It is difficult to diagnose TB in early phase because the symptoms are not specific. The gold standard for TB diagnosis is the culture of M. tuberculosis. It can be performed on a variety of specimens. It is much more sensitive than microscopy but requires more qualified personnel and takes a longer time to provide results. One alternative to support tuberculosis diagnosis is immunochromatographic tuberculosis (ICT Tuberculosis) test. The ICT Tuberculosis test is a test based on the detection of immunoglobulin G (IgG) antibodies directed against antigens secreted by Mycobacterium tuberculosis during active infection. Design and Method: This research used diagnostic test with cross sectional approach. Sampling technique used was a consecutive sampling. Sputum and sera from 27 patients suspected of having pulmonary tuberculosis who visit to Klinik Paru RSUD Prof Dr. Margono Soekarjo Purwokerto were obtained. ICT Tuberculosis test's results were compared with sputum culture. Result: The sensitivity and specificity of the ICT Tuberculosis test were 55,6% and 100%, respectively. Conclusion: The analysis results in this research showed that ICT Tuberculosis test could not be used to diagnosis TB

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