Ovarian stimulation retards postimplantation development and alters global gene expression profile of blastocysts in mouse  

Oleh:

Xinyan, Zhang ; Li, Wang ; Xiuli, Li

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 93 no. 08 (Jun. 2010), page 2770-2773.
Topik: blastocysts

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

This study compares the quality, developmental capacity and global gene expression profile of embryos generated from superovulated and natural cycles. We found that ovarian stimulation impaired quality of blastocysts (cell number: 68.9 ± 6.9 vs. 76.8 ± 7.9; diameter of blastocysts: 145.3 ± 76.9 µm vs. 152.6 ± 65.5 µm), fetus development (rate of development to term: 45.5% vs. 69.1%; weight of 18.5-dpc fetuses: 1.23 ± 0.03 g vs. 1.34 ± 0.03 g) and caused 92 genes differentially expressed.

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