The psychosocial transition associated with spontaneous 46,XX primary ovarian insufficiency: illness uncertainty, stigma, goal flexibility, and purpose in life as factors in emotional health  

Oleh:

Davis, Mary ; Ventura, June L. ; Wieners, Mary

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 93 no. 07 (May 2010), page 2321-2329.
Topik: Primary ovarian insufficiency; hypergonadotropic hypogonadism; premature ovarian failure; premature menopause; infertility; illness uncertainty; stigma; goal flexibility

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Objective To examine factors associated with emotional well-being in women with spontaneous primary ovarian insufficiency. Design Cross-sectional and case–control study. Setting Clinical research center, national U.S. health research facility. Patient(s) Women diagnosed with spontaneous 46,XX primary ovarian insufficiency (n = 100) at a mean age of 32.4 years and healthy control women of similar age (n = 60). Intervention(s) Administration of validated self-reporting instruments. Main Outcome Measure(s) Illness uncertainty, stigma, goal disengagement/re-engagement, purpose in life, Positive and Negative Affect Schedule, Center of Epidemiologic Studies Depression Scale, State-Trait Anxiety Inventory. Result(s) Compared with controls, women with spontaneous primary ovarian insufficiency scored adversely on all measures of affect. Illness uncertainty and purpose in life were significant independent factors associated with anxiety (R2 = 0.47), stigma and purpose in life were the significant independent factors associated with depression (R2 = 0.51), and goal re-engagement and purpose in life were significantly and independently associated with positive affect (R2 = 0.43). Conclusion(s) This evidence supports the need for prospective studies. Our findings are consistent with the hypothesis that clinicians could improve the emotional well-being of their patients with primary ovarian insufficiency by [1] informing them better about their condition, [2] helping them to feel less stigmatized by the disorder, and [3] assisting them in developing alternative goals with regard to family planning as well as other goals.

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