Fertility preservation by ovarian stimulation and oocyte cryopreservation in a 14-year-old adolescent with Turner syndrome mosaicism and impending premature ovarian failure  

Oleh:

Oktay, Kutluk ; Rodriguez-Wallberg, Kenny A. ; Sahin, Gulnaz

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 94 no. 02 (Jul. 2010), page 753.
Topik: Fertility preservation; Turner syndrome; Turner mosaicism; cryopreservation; oocytes; controlled ovarian hyperstimulation; gonadotropins; adolescents

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To report a novel approach to fertility preservation in adolescents with Turner syndrome mosaicism by repeated controlled ovarian stimulation and oocyte cryopreservation. Design Case report. Setting Academic reproductive medicine center. Patient(s) Fourteen-year-old adolescent diagnosed with Turner syndrome mosaicism. Intervention(s) Two cyles of controlled ovarian stimulation and oocyte cryopreservation within 1 year. Main Outcome Measure(s) Recovery of oocytes after controlled ovarian stimulation and oocyte cryopreservation. Result(s) Eleven oocytes were retrieved, of which eight were mature and three were immature during the first cycle. One year later, four mature and three immature oocytes were retrieved after a treatment cycle with even higher gonadotropin doses. All oocytes were cryopreserved by vitrification. Conclusion(s) Controlled ovarian stimulation and oocyte cryopreservation may be an option for fertility preservation in selected adolescents with Turner syndrome mosaicism and impending ovarian failure.

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