Use of F 18-fluoro-D-glucose–positron emission tomography–computed tomography to localize a hilar cell tumor of the ovary  

Oleh:

McCarthy-Keith, Desiree M. ; Hill, Micah ; Norian, John M.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 94 no. 02 (Jul. 2010), page 753.
Topik: Hirsutism; testosterone; hilar cell tumor; FDG-PET/CT

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To describe provocative testing and alternative imaging strategies used to localize an androgen-producing tumor in a 58-year-old woman with severe hirsutism. Design Case report. Setting Clinical Research Center. Patient(s) A 58-year-old woman who was seen for evaluation of severe hirsutism. Intervention(s) Serum androgen levels were measured at baseline, 4 hours after administration of 2000 IU of hCG, and 11 days after administration of 3.75 mg of leuprolide acetate (LA). Magnetic resonance imaging and F 18-fluoro-D-glucose–positron emission tomography–computed tomography (FDG-PET/CT) were performed. Main Outcome Measure(s) Description of preoperative provocative testing and imaging. Result(s) In response to hCG, T rose from 243 to 288 ng/dL then decreased to 233 ng/dL after LA administration. The FDG-PET/CT scan demonstrated focal hypermetabolism in the right pelvis, corresponding to a soft-tissue density on the noncontrast CT scan. Magnetic resonance images were correlated with the PET/CT, and the right ovary was identified. Right salpingo-oophorectomy was performed, and final pathologic examination revealed a hilar cell tumor with ovarian cortical hyperplasia. Conclusion(s) This case demonstrates the utility of provocative testing in the evaluation of a patient with severe hirsutism and illustrates the value of FDG-PET/CT when traditional imaging is nondiagnostic.

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