Uterine artery embolization for fibroids is associated with an increased risk of miscarriage  

Oleh:

Homer, Hayden ; Saridogan, Ertan

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 94 no. 01 (Jun. 2010), page 324-330.
Topik: Uterine artery embolization; UAE; miscarriage; pregnancy; fibroids; myomectomy

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2010.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To investigate how uterine artery embolization (UAE) might alter the risk profile for pregnancies complicated by fibroids. Design Systematic literature review and meta-analysis of existing studies. Setting Academic reproductive medicine unit. Patient(s) Women with fibroids. Intervention(s) A systematic literature review, raw data extraction, and data analysis. Main Outcome Measure(s) Rates of miscarriage, preterm delivery, malpresentation, intrauterine growth restriction (IUGR), cesarean delivery, and postpartum hemorrhage (PPH). Result(s) Two hundred twenty-seven completed pregnancies after UAE were identified. Miscarriage rates were higher in UAE pregnancies (35.2%) compared with fibroid-containing pregnancies matched for age and fibroid location (16.5%) (odds ratio [OR] 2.8; 95% confidence interval [CI] 2.0–3.8). The UAE pregnancies were more likely to be delivered by cesarean section (66% vs. 48.5%; OR 2.1; 95% CI 1.4–2.9) and to experience PPH (13.9% vs. 2.5%; OR 6.4; 95% CI 3.5–11.7). Rates of preterm delivery (14% vs. 16%; OR 0.9; 95% CI 0.5–1.5), IUGR (7.3% vs. 11.7%; OR 0.6; 95% CI 0.3–1.3), and malpresentation (10.4% vs. 13%; OR 0.8; 95% CI 0.4–1.5) were similar in UAE pregnancies and in control pregnancies with fibroids. Conclusion(s) The risk of miscarriage seems to be increased after UAE. In contrast, apart from an increased risk of abdominal delivery and PPH, critical adverse obstetric sequelae of IUGR and prematurity appear no more likely after UAE.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali