COMPARISON OF EPITHELIAL CELL COUNTS BETWEEN MIDDLE AND LATERAL LOBES IN BENIGN PROSTATIC HYPERPLASIA (BPH) PATIENT  

Oleh:

Rahman, Eka Yudha ; Singodimedjo, Prawito

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Jurnal Urologi Indonesia (Indonesian Journal of Urology) vol. 17 no. 01 (Jan. 2010), page 20-24.
Topik: BPH. middle lobe. lateral lobes. HE staining. epithelial cell number

Ketersediaan

Perpustakaan FK Nomor Panggil: J33.K.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective: The aim of this study was to compare the epithelial cell counts in each lobe of prostate glands with benign prostatic hyperplasia (BPH). Material & method: Twenty-two BPH patients who underwent transurethral resection of the prostate (TURP) in Diponegoro Dua Satu Surgery Hospital Klaten, from May until November 2006 were enrolled in this study. Tissue from each lobe of the prostate gland was separately collected.from the middle (A). left lateral (B). right lateral lobes (C), A II samples were fixed in 10% formalin buffer. embedded in paraffin and sectioned in 4 micrometer slices with microtome. After hematoxylin eosin (HE) staining. number of epithelial cells was counted under light microscopy. Difference in epithelial cell coun ts in each alveolus between the three lobes was statisticallv analyzed using t-test (p<0.05). Results: Twenty-two patients were included in this study from May 10 November 2006. mean age was 66.64±7.6 (54-88) years old. The most common occupation was farmer Almost all patients had symptoms of chronic urinarv retention (95.45'%), Length of hospital stay was 8. 77±2. 7 (6-17) days. mean weight of prostate resected was 47. 05±23.2 (5-90) grams. mean operative time 77.7 3±22.24 (45-11 5) minute. mean volume of irrigation fluid (sterile water) was 24.1 8±7.8 7 (5-34) liter Mean number of cells in groups A, B, and C were 23. 6 7±8.4 ( 13,6-44.4), 29.22±8.8 (16.4-41,2). and 29.11~8, 7 (16. 4-41.2) respectively. There was significant difference between groups A and B. and between groups A and C (p<0.05) respectively Conclusion: There was statistically significant difference in epithelial cell count between the middle lobes compared to lateral lobes of the prostate in BPH surgical samples. These findings are supported by cystoscopic observation of smaller middle lobe compared to the lateral lobes in BPH.

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