EFIKASI TAMSULOSIN PADA BENIGN PROSTATIC HYPERPLASIA DENGAN RETENSIO URINE AKUT YANG MENJALANI TRIAL WITHOUT CATHETER  

Oleh:

Kholis, Khoirul ; Soetojo ; Tarmono ; Widodo, JP

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Jurnal Urologi Indonesia (Indonesian Journal of Urology) vol. 16 no. 02 (Jul. 2009), page 48-52.
Topik: Benign prostate hyperplasia; tamsulosin; trial without catheter; urine retention

Ketersediaan

Perpustakaan FK Nomor Panggil: J33.K.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective: To evaluate the efficacy of tamsulosin on BPH patients with an acute urine retention on a trial without catheter (TWOC). Materials & methods: This study was a post test only-placebo group design comparing residual urine in BPH patients with an acute urine retention on TWOC between groups treated with tamsulosin and placebo. The efficacy with tamsulosin or placebo on the 3rd and 14th day was analyzed using the Chi square test and Me Nemar test. Results: This study showed that there was still urine retention in 7 patients (58.3%) and 4 patients (44,4%) shared recovery within 3 days of tamsulosin administration. while 5 patients (41,7%) still had urine retention compared to 5 patients (55,6%) who showed recovery in the placebo group. The difference was insignificant with p=0. 67. Patients who dropped out from TWOC on the 3rd day and given tamsulosin until the 14th day showed still urine retention in 4 patients (44,4%) and recovery in 3 patients (100%) while all samples who were given placebo showed urine retention in 5 patients (55,6%). The difference was insignificant with p=0. 205. Follow up for 3 days in the tamsulosin group with urine retention. 3 patients became free from urine retention and the other 4 patients still had it. However in this study. no difference in efficacy (p= 1.025). In placebo groups with urine retention before the 3rd day of administration still showed urine retention after the 14th day. Conclusion: There was no statistical differences on the success of TWOC, between groups given 0.2 mg of tamsulosin and the placebo group. neither on the 3rd day noron the 14th day. There was reduction of recatheterization because of failure of TWOC with patients who were given tamsulosin for 14 days.

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