HUBUNGAN TGF-ß1 DAN ESTROGEN DENGAN VOLUME PROSTAT PADA PASIEN BPH, PASIEN TUA NON BPH, DAN PASIEN MUDA  

Oleh:

Soebhali, Boyke ; Soetojo ; Soebadi, Doddy M.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Jurnal Urologi Indonesia (Indonesian Journal of Urology) vol. 16 no. 01 (Jan. 2009), page 6-10.
Topik: TGF-ß1; Estrogen; BPH

Ketersediaan

Perpustakaan FK Nomor Panggil: J33.K.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective: To determine the correlation of TGF-ß1 and estrogen with prostate volume in BPH patients. old patients without BPH and young patients. Materials and methods: We enrolled 30 patients and allocated them into three groups. First group consists of BPH patients, second group consists of old m ale patients with more than 55 years of age, and third group consists of young male patients with less than 40 years of age. We analyzed the level of TGF-ß1 and estrogen in these patients. Transrectal USG was used to measure the prostate volume. We analyzed the correlations of TGF-ß1 and estrogen level with prostate volume. Results: We found a positive strong correlation between estrogen and prostate volume in the BPH patient group (p=0,021: r coeff'=0,786). Other group showed no significant correlations. Conclusion: Estrogen plays an important role in BPH pathophysiology. Further research on the influence of estrogen in BPH patients is recommended.

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