The decline in sensory acuity, especially in the sense of sight is very harmful, especially on working conditions. Weakness is impacting response to worker safety, the quality of the finished product is unsatisfactory because it passes inspection Therefore there should be an investigation to find out the main cause of the decline in the quality of one's response. This study considers three main factors believed to result in lower response of a person, the age factor, the factor of lighting levels and gender factors. This research was conducted in two different conditions that is when the respondents in a fit condition and the condition of tired. After collecting data by experimenting reaction time test, performed data analysis through experimental design approach covers ANOVA and Post Hoc Test. The results of the data processing states that the factors that significantly influence is a factor that has a sig value is smaller than the value of a of 0.05. The factors that affect significantly is the age factor and the factor of lighting levels. Gender factor is not statistically significant. Covariate factors (type of work, glasses, visual disturbances, sleep, exercise, and gym) have an influence on reaction time. The factors that influence the lighting level factors and factors of age. This indicates that the covariate factors did not produce a significant effect on the results of reaction time. |