Pneumonitis Radiasi pada Penderita Karsinoma Payudara yang Mendapat Terapi Kemoradiasi di RSUP Dr. Kariadi  

Oleh:

Fatchoerochman ; Zulqarnain, Nasirun ; Kuntjoro, Eko

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI - non-atma jaya
Dalam koleksi: Media Medika Indonesiana vol. 44 no. 01 (Jan. 2010), page 37-43.
Topik: Radiation pneumonitis incidence; breast cancer

Ketersediaan

Perpustakaan FK Nomor Panggil: M30.K.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: The diagnosis of radiation pneumonitis relied on clinical symptoms and chest x-ray. Radiation pneumonitis will arise 6 to 12 week after external radiation therapy was completed, combination with chemotherapy will increase risk factor of radiation pneumonitis. The aim of this research is to find incidence of radiation pneumonitis among the breast cancer patient with chemoradiation therapy. Method: This study was an analitic descriptive, with subjects were patients with stage II-III breast carcinoma that have finished chemoradiation therapy at Dr. Kariadi hospital from Januari 1st 2007 to March 31st 2009. They were contacted by telephone or came for control. Radiation was given with dosage of 50 Gy and booster 10 Gy on chest wall. Incidence data of radiation pneumonitis was analyzed. Result: The mean age was 48.7 years. The incidence of radiation pneumonitis was 13 from 32 subjects (40.6%), with 69% was in mild degree. As much as 31.3% used CAF regiment, 55.6% CAF-xeloda regiment, 20.0% CEF regiment, and xeloda + CEF-xeloda was 100%. There was no significant difference of radiation pneumonitis proportion based on age (p=0.09) and stadium (p=0.15). Most of the patients examined by chest x-ray with pulmonary symptoms, while those with no pulmonary symptom disapproved to be taken the chest x-ray. This caused the selection bias, thus the incidence of radiation pneumonitis tend to be high. Conclusion: There were high tendency (40.6%) of radiation pneumonitis incidence at stage II-III breast cancer patient who get chemoradiation therapy at Dr. Kariadi General Hospital, but the most degree of radiation pneumonitis is mild.

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