Detail Aktivitas Antifungal Madu Hutan Tesso Nilo (MHTN) terhadap Candida albicans secara In Vitro Bibliografi Author: PUTRA, YENNI ; Sahusilawane, Isadora Gracia (Advisor); Yolanda, Hanna (Advisor); Joprang, Freggy Spicano (Examiner) Topik: ANTIBIOTICS; antifungal; Candida albicans; macrodilution; Tesso Nilo Wild Honey; madu hutan Tesso Nilo; makrodilusi Bahasa: (ID )     Penerbit: Fakultas Kedokteran Unika Atma Jaya     Tempat Terbit: Jakarta Utara    Tahun Terbit: 2014     Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK) Fulltext: Yenni_Putra_KTI_2014.pdf (14.45MB; 8 download) Ketersediaan Perpustakaan FK Nomor Panggil: KTI-FK-677 Non-tandon: tidak ada Tandon: 1  Lihat Detail Induk Abstract Introduction Candida sp. is a normal flora inhabiting the human skin and mucosa. In certain conditions, Candida sp. may cause a disease called candidiasis. Candida albicans,as the main pathogen in 65% candidiasis cases, had recently show increased in resistancy toward fluconazole and voriconazole.Candidiasis is one of the disease that is found in immunocompromised patients. Candidiasis among immunocompromised patient often requires a long term usage of antifungal agents to prevent it’s recurrance. The long term usage of antifungal agents may cause harmful side effects. Honey is used as an alternative antifungal agent that had been proven by researches. Tesso Nillo Wild Honey which originated from Tesso Nilo National Park account as one of the Green and Fair Product byWorld Wildlife Fund (WWF)Indonesia, so the quality of this honey can be guaranteed. This study is performed with the aim of investigating the antifungal activity of Tesso Nillo Wild Honey against Candida albicans in vitro. Methods This is an experimental in vitro study using the macrodilution method. The main idea of the study is to compare the quantity of Candida albicansnumbers of colony in each test group with concentration of Tesso Nillo Wild Honey of 250 mg/mL, 500 mg/mL, 750 mg/mL and 1000 mg/mLwith the positive control of Candida albicans in Sabouroud Dextrose Broth. Results Results are processed with SPSS using the Kruskal-Wallis statistic test and continued with the Post Hoc Mann-Whitney statistic analysis. The test group with the concentration of 500 mg/mL and 750 mg/mL had significant difference if compared with the positive control with p equals to 0,043 and 0,046 respectively. Conclusion Tesso Nillo Wild Honey has an antifungal activity against Candida albicans in vitro according to the macrodilution method. The test group with the concentration of 500 mg/mL shows an optimal result with the significant difference in numbers of colony quantity. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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