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Deep Vein Thrombosis in Acute Myelogenous Leukemia
Oleh:
Oehadian, Amaylia
;
Iqbal, Mohammad
;
Sumantri, Rachmat
Jenis:
Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi:
Acta Medica Indonesiana vol. 41 no. 04 (Oct. 2009)
,
page 200-204.
Topik:
deep vein thrombosis. leukemia. hemorrhage
Ketersediaan
Perpustakaan FK
Nomor Panggil:
A02.K.02
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Thrombotic complications in acute leukemia are often underestimated because bleeding complications generally dominate the clinical picture. While there are many thrombogenic factors shared by both solid tumors and leukemia. many additional prothrombotic features are present in leukemia. The prothrombotic factors include hyperleukocytosis, increased expression of tissue factor and its activation in leukemic cells. and the pro thrombotic adverse effects of therapeutic agents and vascular access cathethers. A 18-year old woman came with swelling on her right leg 10 days before hospital admission. Since 2 months before she had had weakness, pallor and fever without bleeding manifestation. Hematologic examinations showed anemia. leukocytosis with monoblast and thrombocytope-nia. Deep vein thrombosis in right femoral and right popliteal vein was confirmed using compression ultrasonography. The treatment of such complications is challenging because of the high risk of hemorrhage in this group of patients. especially due to their severe thrombocytopenia.
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