Antibody anti-H5N1 detection in poultry farmers and workers in poultry collection facilities in Indonesia, 2007  

Oleh:

Setiawaty, Vivi ; Sedyaningsih, Endang R. ; Sudiro, Tjahyani M.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Medical Journal of Indonesia vol. 19 no. 02 (May 2010), page 124-129.
Topik: Avian influenza; farmers; poultry workers; seropositive

Ketersediaan

Perpustakaan FK Nomor Panggil: M35.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Aim Between July 2005 and May 2008, Indonesia reported 133 H5Nl confirmed human cases with a case fatality proportion of 81 %. Fifty-four percent of cases had a history of direct contact with poultry (chickens). Therefore, it is important to define the detection of antibody of H5Nl among people who have intensive contact with poultry have been exposed to H5Nl viruses. Methods We collected sera from healthy poultry-collecting-facility (PCF) workers in Jakarta and healthy poultry¬-farmers in Sukabumi which have close contact with poultry. Anti-H5Nl antibodies were tested with modified Haemagglutination Inhibition (HI) assay using A/Ck/Banten/05-1 1 16/05(H5Nl) antigen and with Neutralization (NT) assay using A/H5Nl/lndo/05/lBCDC-RG virus. Results Among the 216 PCF worker sera and the 495 poultry-farmer sera that we collected, we found that all poultry-¬farmers were seronegative and one percent of poultry-collecting-facilities workers were seropositive by both HI and 1 % by NT assays. Conclusions This study detected asymptomatic H5Nl virus infection among poultry workers in PCFs with intensive contact with various

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