RAGAM BERBAGAI PERBENIHAN BAKTERI TERKAIT KERENTANANNYA TERHADAP ANEKA JENIS ANTIBIOTIKA  

Oleh:

Viany S, Carolina M ; Aryati

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Clinical Pathology and Medical Laboratory vol. 16 no. 02 (Mar. 2010), page 62-64.
Topik: Various bacterial cultures; Susceptibility; Antibiotics

Ketersediaan

Perpustakaan FK Nomor Panggil: I01.K.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Infection is the major public health problem in Indonesia which could increase its morbidity and mortality. The antibiotics treatment which were given irrationally leads to bacteria susceptibility and worsen the problem. One of the efforts to manage the bacteria susceptibility the physician has to know the bacterial pattern and its characteristic to resist various antibiotics. The information may contribute as a reference to give antibiotic therapy in a rational mann er. To know the bacterial susceptibility pattern against various antibiotics a study was carried out using specimens derived from several hospitals which referred them to a private laboratory in Surabaya. The specimens consisted of blood, urine and sputum were referred during September 2007 up to July 2008. The identiftcation of the bacteria and it's susceptibility pattern were carried out by a conventional method and an auto analyzer (Vitek 2 Compact). The antibiotic susceptibility test was carried out by conventional method using Kirby Bauer modifiied diffusion technique and Vitec 2 Compact using MIC reference. The results showed that the most common bacteria found from blood was Escherichia coli which was still sensitive to amoxicillin-clavulanic acid, amikacin, and cefepim. And from the urine was Escherichia coli which were still sensitive to meropenem followed by amikacin and gentamycin. Whereas from the sputum was found Streptococcus a haemolyticus which was still sensitive to amoxicillin-clavulanic acid, piperacillin tazobactam, linezolid. The result of the antibiotic susceptibility test is mostly dominated by the Betalactam group, such as amoxicillin-clavulanic acid and carbapenem group like meropenem. Besides of thai, in th is study was also found multiple drug resistance organis ms (MDRO), such as Escherichia coli ESBL, Enterobacter liquefaciens ESBL, Enterobacter agglomerans ESBL, Klebsiella ozaenae ESBL, and Klebsiella pneumoniae ESBL. The susceptibility pattern of the bacteria derived from blood and sputum is dominated by gram positive cocci. Whereas from urine is dominated by Gram negative rods.

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