Detail Review: Hepatitis C Virus, Autoimmunity and Rheumatic Disease   Oleh:  Buskila, D. ; Sikuler, E. ; Shoenfeld, Y. Jenis: Article from Journal Dalam koleksi: Lupus vol. 6 no. 9 (1997), page 685-689. Topik: Hepatitis C Virus Fulltext: 685.full.pdf (516.08KB) Isi artikel In 1989, the existence of hepatitis C virus (HCV) was established’ and it was recognized as the major causative agent of non-A, non-B hepatitis.2,3 HCV is a single stranded RNA virus which is considered to be a member of a distinct genus in the flaviviridae family. Based on nucleic acid sequence analysis, six major genotypes and more closely related subtypes have been identified.’ Variability is distributed throughout the genome, with the non-structural genes of different genotypes showing 65-70% homology. Genotypes 1, 2 and 3 are widely distributed throughout Western countries and the Far East. Types 5 and 6 are largely confined to South Africa and South East Asia, respectively, whereas type 4 is found predominantly in the Middle East and Central Africa.44 Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

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