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Expression of Anti-DNA Antibodies
Oleh:
Silverman, G.J.
;
Stevenson, F.K.
Jenis:
Article from Journal
Dalam koleksi:
Lupus vol. 6 no. 3 (1997)
,
page 321-323.
Topik:
Autoantibodies
;
Phage Expression
;
Idiotypes
;
Molecular Mimicry
Fulltext:
321.full.pdf
(334.3KB)
Isi artikel
This session was concerned with the question of molecular recognition of target autoantigen by anti- DNA antibodies. To probe potentially pathogenic sequences in the antibodies it is necessary to establish efficient and reproducible expression systems. Several of these were discussed, and the biological activities of constructed antibodies reported. Clearly, the molecular tools for understanding the destructive potential of autoantibodies are now available.
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