Systemic Lupus Erythematosus with Acanthosis Nigricans, Hyperpigmentation, and Insulin Receptor Antibody  

Oleh:

Baird, J.S. ; Johnson, J.L. ; Mills, D. Elliott ; Opas, L.M.

Jenis: Article from Journal
Dalam koleksi: Lupus vol. 6 no. 3 (1997), page 275-278.
Topik: Acanthosis Nigricans; Hyperpigmentation; Lupus Erythematosus; Systemic; Insulin Resistance
Fulltext: 275.full.pdf (477.17KB)

Isi artikel

Acanthosis nigricans, insulin receptor antibody, and systemic lupus erythematosus are associated in the potentially lethal syndrome of type B insulin resistance. Hyperpigmentation has been reported rarely, while glucose intolerance is common in these patients. We report an adolescent girl with acanthosis nigricans, hyperpigmentation, insulin receptor antibody, and systemic lupus erythematosus without glucose intolerance. Insulin resistance may be mild or transient in some patients with type B insulin resistance. Resolution of skin lesions was noted during therapy of SLE, and was associated with disappearance of insulin receptor antibody.

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