The Impact of Early Diastolic Myocardial Relaxation on the Other Parameters of Diastolic Function and Association of Tissue Doppler Parameters of Diastolic Function with Diabetes Compensation and Duration in Type 2 Diabetic Patients  

Oleh:

Charvat, J. ; Chlumsky, J. ; Svab, P ; Zamrazil, V

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 38 no. 01 (Jan. 2010), page 127-133.
Topik: diabetes mellitus; diastolic function; tissue doppler echocardiography

Ketersediaan

Perpustakaan FK Nomor Panggil: J11.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

This study assessed the impact of tissue Doppler derived myocardial early diastolic relaxation velocity (Em) on the other parameters of diastolic function (preload dependent transmitral early diastolic velocity [E], tissue Doppler derived myocardial late diastolic velocity [Am], preload dependent transmitral late diastolic velocity [A]) and evaluated the correlation of these parameters with selected clinical variables in type 2 diabetic patients. Using tissue Doppler echocardiography, 82 type 2 diabetic patients were evaluated, divided into two equal groups of Em less than 7.5 cm/s or equal to or greater than 7.5 cm/s. Patients with Em less than 7.5 cm/s had significantly lower E/A and Em/Am, and higher E/Em values. Multilinear regression showed a negative correlation between Em and glycated haemoglobin (HbA1c) and duration of diabetes, a negative correlation of Em/Am with age, duration of diabetes and HbA1c, and a positive correlation of E/Em with age, duration of diabetes and use of diuretics. The E/A ratio only correlated negatively with age. It is concluded that Em is a reliable parameter of diastolic function, and that the tissue Doppler parameters of diastolic function are associated with diabetes compensation and diabetes duration.

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